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A protein found only in horseshoe crab blood is the pharmaceutical industry standard for testing for impurities in medicines, especially injectables. As a result of this, the population of horseshoe crabs is threatened as 600,000 per year are caught in the wild, harvested for blood in laboratories, and released back into the wild either to die or hopefully live on. One gallon of horseshoe crab blood is valued at about $30,000.
A research team local to Frederick, MD has developed a means to grow this protein in a laboratory, from horseshoe crab muscle cells. With the cells from one leg of one crab (the crab will actually regenerate the leg), the laboratory can grow as much of the desired protein as all of the blood harvested annually from the 600,000 crabs that are caught and bled in laboratories. As an added benefit, all of the protein generated is genetically identical- this is a great advantage to the pharmaceutical companies.
Imagine the benefit of being able to grow this protein in a lab as opposed to relying on harvesting horseshoe crabs. This research team has at once enabled a technology that promises to lower the cost of pharmaceuticals, improve the quality and of testing for impurities in pharmaceuticals and to rescue an ancient species from extinction.
The process to grow the protein has been demonstrated and the protein that was produced is under test at several large pharmaceutical companies. The process for producing the protein is proprietary and well-protected within the small research team.
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